Absorbed dose estimations of <SUP>131</SUP>I for critical organs using the GEANT4 Monte Carlo simulation code

Ziaur Rahman; Shakeel ur; Waheed Arshed; Nasir M; Abdul Rashid; Jahan Zeb

doi:10.1088/1674-1137/36/11/021

Chinese Physics C> 2012, Vol. 36> Issue(11) : 1150-1156 DOI: 10.1088/1674-1137/36/11/021

Absorbed dose estimations of ¹³¹I for critical organs using the GEANT4 Monte Carlo simulation code

Abstract
HTML
Reference
Related

PDF

Abstract：
The aim of this study is to compare the absorbed doses of critical organs of ¹³¹I using the MIRD (Medical Internal Radiation Dose) with the corresponding predictions made by GEANT4 simulations. S-values (mean absorbed dose rate per unit activity) and energy deposition per decay for critical organs of ¹³¹I for various ages, using standard cylindrical phantom comprising water and ICRP soft-tissue material, have also been estimated. In this study the effect of volume reduction of thyroid, during radiation therapy, on the calculation of absorbed dose is also being estimated using GEANT4. Photon specific energy deposition in the other organs of the neck, due to ¹³¹I decay in the thyroid organ, has also been estimated. The maximum relative difference of MIRD with the GEANT4 simulated results is 5.64% for an adult's critical organs of ¹³¹I. Excellent agreement was found between the results of water and ICRP soft tissue using the cylindrical model. S-values are tabulated for critical organs of ¹³¹I, using 1, 5, 10, 15 and 18 years (adults) individuals. S-values for a cylindrical thyroid of different sizes, having 3.07% relative differences of GEANT4 with Siegel & Stabin results. Comparison of the experimentally measured values at 0.5 and 1 m away from neck of the ionization chamber with GEANT4 based Monte Carlo simulations results show good agreement. This study shows that GEANT4 code is an important tool for the internal dosimetry calculations.

References

[1]

Clarke SEM. Clinical Oncology, 2010, 22: 430-437[2] Dawson P, Punwani S. European J of Radiology, 2009, 69: 74-79[3] Green D M, Hyland A, Barcos M P et al. J Clin. Oncl., 2000, 18(7): 1492-1497[4] Bielajew A, Rogers D. Nucl. Instrum. Methods B, 1987, 18: 165-181[5] Briesmeister J F, ed. MCNP-A General Monte Carlo N-Particle Transport Code, Version 4C. Los Alamos National Laboratory, 2000, LA-13709-M[6] Johnson T K. Comp. Methods Programs Biomed, 1988, 27: 159-167[7] Stabin M G, Flux G D. Biomed Imaging Interv J, 2007, 3(2): e 28[8] Sergio Lo Meo, Gianfranco Cicoria, Giancarlo Montini et al. Nuclear Medicine Communications, 2008, 29: 1100-1105[9] Mowlavi A A, Fornasier M R, de Denaro Mario. Radiol Oncol, 2011, 45(2): 143-146[10] Amato E et al. Absorbed Fractions in Ellipsoidal Volumes for Beta Radionuclide's Employed in Internal Radiotherapy Phys. Med. Biol., 2009, 544171-544180[11] Amako K, Guatelli S, Ivanchencko V et al. Nucl. Physics B, 2006, 150, 44-49[12] Siegel J A, Stabin M G. J Nucl. Med., 1994, 35: 52-56[13] Agostinelli S, Allison J, Amako K et al. Instrum. Methods A, 2003, 506: 250-303[14] Allison J. IEEE Trans. Nucl. Sci., 2006, 53: 270-278[15] International Commission on Radiological Protection. Radiation Doe to Patients from Radiopharmaceutical. Publication 53. Annals of ICRP, 18, No. 1-4, Pergmon Press, 1988[16] Snyder W S, Ford M R, Warner G G, Watson S B. MIRD Pamphlet No. 11: "S" Absorb dose per Unit Cumulated Activity for Selected Radionuclide's and Organs. New York: Society of Nuclear Medicine, 1975[17] Cember H, Thomas E. Johason, Introduction to Health Physics. New York: McGraw-Hill, 2009[18] Biodex Medical Systems, 043-365 Uptake Neck Phantom Manufacturer Specifications, 2012[19] Kadri O, Gharbi F, Farah K, Mannai K, Trabelsi A, Applied Rad and Isot, 2006, 64: 170-177[20] Ellett W H, Humes R M. J Nucl. Med., 1971, 12(Suppl 5): 25-32[21] Brownell G L, Ellen W H, Reddy A R. The Society of Nuclear Medicine: MIRD Pamphlet 3. J Nucl. Med., 1968, 9(suppl l): 27-39[22] Cirrone G A P, Cuttone G, Rosa F Di. Nucl. Instrum. Methods in Physics A: 2010, 618: 315-322[23] Triono A C, di Martino F, Lazzeri M, Stabin M G. Phys. Med. Biol., 2000, 45: 121-129

[1]	XU Hai-Bo , ZHENG Na . Monte Carlo simulation and parameterized treatment on the effect of nuclear elastic scattering in high-energy proton radiography. Chinese Physics C, 2015, 39(7): 078201. doi: 10.1088/1674-1137/39/7/078201
[2]	ZHENG Na , XU Hai-Bo . Transmission calculation by empirical numerical model and Monte Carlo simulation in high energy proton radiography of thick objects. Chinese Physics C, 2015, 39(10): 108201. doi: 10.1088/1674-1137/39/10/108201
[3]	PANG Cheng-Guo , SU You-Wu , WANG Wen-Jun , LUO Xiao-Ming , XU Jun-Ku , LI Wu-Yuan , YUAN Jiao , YAO Ze-En . Monte Carlo simulation of carbon ion radiotherapy for the human eye. Chinese Physics C, 2015, 39(1): 018201. doi: 10.1088/1674-1137/39/1/018201
[4]	WANG Wen , CHENG Meng-Yun , LONG Peng-Cheng , HU Li-Qin . Specific absorbed fractions of electrons and photons forRad-HUMAN phantom using Monte Carlo method. Chinese Physics C, 2015, 39(7): 078203. doi: 10.1088/1674-1137/39/7/078203
[5]	LI Cheng-Bo , WEN Qun-Gang , ZHOU Shu-Hua , JIANG Zong-Jun , FU Yuan-Yong , ZHOU Jing , MENG Qiu-Ying , WANG Xiao-Lian . Experimental spectra analysis in THM with the help of simulation based on the Geant4 framework. Chinese Physics C, 2015, 39(5): 054001. doi: 10.1088/1674-1137/39/5/054001
[6]	QU Wei-Wei , ZHANG Gao-Long , GUO Chen-Lei , LE Xiao-Yun . Simulation of beam optics for ¹²C+¹²C scattering of RCNP by using Monte Carlo method. Chinese Physics C, 2014, 38(11): 116202. doi: 10.1088/1674-1137/38/11/116202
[7]	ZHANG Jin-Zhao , TUO Xian-Guo . A Monte Carlo simulation and setup optimization of output efficiency to PGNAA thermal neutron using ²⁵²Cf neutrons. Chinese Physics C, 2014, 38(7): 078201. doi: 10.1088/1674-1137/38/7/078201
[8]	DENG Jun , CAO Lei , SU Xu . Monte Carlo simulation of indoor external exposure due to gamma-emitting radionuclides in building materials. Chinese Physics C, 2014, 38(10): 108202. doi: 10.1088/1674-1137/38/10/108202
[9]	Ziaur Rahman , Sikander M , Waheed Arshed , Nasir M , Waheed Ahmed . Influence of thyroid volume reduction on absorbed dose in ¹³¹I therapy studied by using Geant4 Monte Carlo simulation. Chinese Physics C, 2014, 38(5): 056201. doi: 10.1088/1674-1137/38/5/056201
[10]	ZHANG Su-Ya-La-Tu , CHEN Zhi-Qiang , HAN Rui , LIU Xing-Quan , LIN Wei-Ping , JIN Zeng-Xue , XI Yin-Yin , LIU Jian-Li , SHI Fu-Dong . Study on gamma response function of EJ301 organic liquid scintillator with GEANT4 and FLUKA. Chinese Physics C, 2013, 37(12): 126003. doi: 10.1088/1674-1137/37/12/126003
[11]	ZHANG Hui , SHAO Ming , LI Cheng , CHEN Hong-Fang , HENG Yue-Kun , SUN Yong-Jie , TANG Ze-Bo , JI Chang-Sheng , CHEN Tian-Xiang , YANG Shuai . A GEANT4 simulation study of BESⅢ endcap TOF upgrade. Chinese Physics C, 2013, 37(9): 096002. doi: 10.1088/1674-1137/37/9/096002
[12]	TANG Xiao , ZHAO Wei , WANG Yan-Fang , SHU Hang , SUN Cui-Li , WEI Cun-Feng , CAO Da-Quan , QUE Jie-Min , SHI Rong-Jian , WEI Long . Monte Carlo simulation of glandular dose in a dedicated breast CT system. Chinese Physics C, 2012, 36(7): 675-680. doi: 10.1088/1674-1137/36/7/019
[13]	GUO Yi-Qing , ZHANG Xue-Yao , ZHANG Jian-Li , HU Hong-Bo , ZHA Min , HE Hui-Hai , FENG Zhao-Yang , WU Chao-Yong , WANG Bo , ZHANG Yi , LU Hong . ARGO-YBJ detector simulation using GEANT4. Chinese Physics C, 2010, 34(5): 555-559. doi: 10.1088/1674-1137/34/5/008
[14]	SONG Yu-Shou , YE Yan-Lin , GE Yu-Cheng , LÜ Lin-Hui , Faisal Q. , JIANG Dong-Xing , HUA Hui , ZHENG Tao , LI Zhi-Huan , LI Xiang-Qing , LOU Jian-Ling , LU Fei , FAN Feng-Ying , CAO Zhong-Xin , LI Qi-Te , XIAO Jun . Monte Carlo simulation of the property of a scintillation bar in the multi-neutron correlation spectrometer. Chinese Physics C, 2009, 33(10): 860-865. doi: 10.1088/1674-1137/33/10/008
[15]	J. T. Rhee , Y. J. Jeon . Study of neutron response for two hybrid RPC setups using the GEANT4 MC simulation approach. Chinese Physics C, 2009, 33(10): 887-891. doi: 10.1088/1674-1137/33/10/012
[16]	YOU Zheng-Yun , LIANG Yu-Tie , MAO Ya-Jun . A method for detector description exchange among ROOT GEANT4 and GEANT3. Chinese Physics C, 2008, 32(7): 572-575. doi: 10.1088/1674-1137/32/7/012
[17]	ZHANG Li-Ming , PENG Hai-Ping , SHAO Ming , ZHANG Zi-Ping , CHEN Hong-Fang , WU Jian . Single TOF Scintillation Counter Simulation Study with GEANT4. Chinese Physics C, 2003, 27(12): 1109-1113.
[18]	Yao Xiaoxia , Zhao Weiqin , Pang Yang . Monte Carlo Simulation of J/ψ Suppression Based on GCP Code. Chinese Physics C, 1999, 23(6): 536-545.
[19]	Huang Yinzhi , Cheng Baosen , Liu Huaimin , Ma Aimin , Xiong Weijun , Fan Xiaoling , Qi Nading , Zhang Dahua , Chen Shaomin , Xie Yuehong , Li Haibo , Hu Jingliang , Zhang Jinlong . Development and Application of the Fast Monte Carlo Simulation Method for Beijing τ-Charm Factory (BTCF). Chinese Physics C, 1997, 21(S3): 17-28.
[20]	Sa Benhao , Yang Xiazhou , Bai Xixiang . Transport Theory Approach to Parton Multiple Scattering in Nuclei---Monte Carlo Simulation. Chinese Physics C, 1988, 12(S2): 175-180.

Access

Get Citation

Ziaur Rahman, Shakeel ur, Waheed Arshed, Nasir M, Abdul Rashid and Jahan Zeb. Absorbed dose estimations of ¹³¹I for critical organs using the GEANT4 Monte Carlo simulation code[J]. Chinese Physics C, 2012, 36(11): 1150-1156. doi: 10.1088/1674-1137/36/11/021

RIS(for EndNote,Reference Manager,ProCite)

BibTex

Txt

Milestone

Received: 2012-02-13
Revised: 1900-01-01

Article Metric

Article Views(2054)
PDF Downloads(313)
Cited by(0)

Policy on re-use

To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Absorbed dose estimations of ¹³¹I for critical organs using the GEANT4 Monte Carlo simulation code

Abstract：

References

Access

Article Metrics

Metrics

通讯作者: 陈斌, bchen63@163.com

Email This Article

Absorbed dose estimations of ¹³¹I for critical organs using the GEANT4 Monte Carlo simulation code

HTML

目录

Absorbed dose estimations of 131I for critical organs using the GEANT4 Monte Carlo simulation code

Abstract：

References

Access

Article Metrics

Metrics

通讯作者: 陈斌, bchen63@163.com

Email This Article

Absorbed dose estimations of 131I for critical organs using the GEANT4 Monte Carlo simulation code

HTML

目录

Absorbed dose estimations of ¹³¹I for critical organs using the GEANT4 Monte Carlo simulation code

Absorbed dose estimations of ¹³¹I for critical organs using the GEANT4 Monte Carlo simulation code