Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations

LI Qiang

Chinese Physics C> 2005, Vol. 29> Issue(10) : 1006-1011

Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations

LI Qiang ^,

Institute of Modern Physics,Chinese Academy of Sciences,Lanzhou 730000,China2 German Heavy-Ion Research Center GSI,Darmstadt 64291,Germany

Abstract
HTML
Reference
Related

PDF

Abstract：
Within the framework of the pilot heavy-ion therapy facility at GSI equipping an active beam delivery system of advanced raster scanning technique, the investigation of actively conformal irradiation to moving tumors using heavy ions is underway. The influences of target motion on dose homogeneity and conformity degree were theoretically studied under the condition of the active raster-scanning beam delivery system.The relationship between the target motion with different patterns and the uniformities of doses delivered by the raster scanner to different iso-energy slices of the moving target were simulated with an experimentally measured beam spill. Several strategies improving the dose homogeneity in the moving target volume were derived from these simulation results. The simulations presented in this paper provide an effective means for evaluating the dose distribution for a moving target, and the results and implications of this theoretical work establish a substantial basis for feasibility experiments of the compensation for target motion with the active raster scanner at GSI.

References

[1]

. Schulz-Ertner D, Nikoghosyan A, Thilmann C et al. Int. J. Radiat. Oncol. Biol. Phys., 2004, 58: 631—6402. Haken R, Balter J, Marsh L et al. Int. J. Radiat. Oncol. Boil. Phys., 1997, 38: 613—6173. Okumura T, Tsuji H, Tsujii H. Compensation of Target Motion. In: Ion Beams in Tumor Therapy. Linz U Ed. London: Chapman and Hall, 1995, 308—3154. Wong J, Sharpe M, Jaffray D et al. Int. J. Radiat. Oncol. Biol. Phys., 1999, 44: 911—9195. Ohara K, Okumura T, Akisada M et al. Int. J. Radiat. Oncol. Biol. Phys., 1989, 17: 853—8576. Kubo H D, Hill B C. Phys. Med. Boil., 1996, 41: 83—917. Minohara S, Kanai T, Endo M et al. Int. J. Radiat. Oncol. Biol. Phys., 2000, 47: 1097—11038. Haberer T, Becher W, Schardt D et al. Nucl. Instrum. Methods, 1993, A330: 296—3059. Kraft G. Prog. Part. Nucl. Phys., 2000, 45: S473—S54410. Shimizu S, Shirato H, Aoyama H et al. Int. J. Radiat. Oncol. Biol. Phys., 2000, 48: 471—47411. Yu C X, Jaffray D A, Wong J W. Phys. Med. Boil., 1998,43: 91—10412. Kraemer M et al. Phys. Med. Biol., 2000, 45: 329913. Kraemer M, Scholz M. Phys. Med. Biol., 2000, 45: 331914. Schlegel W, Pastyr O, Bortfeld T et al. Int. J. Radiat. Oncol. Biol. Phys., 1992, 24: 781—78715. Brusasco C et al. Nucl. Instrum. Methods, 2000, B168:57816. Li Q et al. Phys. Med. Biol., 2004, 49: 302917. Weber U, Becher W, Kraft G. Phys. Med. Biol., 2000, 45:3627—364118. Phillips M H et al. Phys. Med. Biol., 1992, 37: 22319. Spielberger B et al. Phys. Med. Biol., 2001, 46: 2889

[1]	ZHAO Jie , PENG Shi-Xiang , LU Yuan-Rong , GUO Zhi-Yu . Control System of a Low-Energy High-Current Ion Beam Transport Test Bench. Chinese Physics C, 2008, 32(S1): 115-117.
[2]	SUN Da-Rui , XU Jin-Qiang , TANG Kun . Simulation and Error Analysis of Electro-optic Sampling Measurement of Ultrashort Electron Beam Bunch Length. Chinese Physics C, 2008, 32(S1): 121-123.
[3]	M.P.Stockli . Measuring and Analyzing Transverse Low-Energy Ion Beam Emittances. Chinese Physics C, 2007, 31(S1): 182-186.
[4]	J.P.Briand . Applications of Highly Ionized Ion Beams (abstract only). Chinese Physics C, 2007, 31(S1): 236-236.
[5]	MAO Li-Jun , YANG Xiao-Dong , XIA Jia-Wen , WEI Bao-Wen . Intrabeam Scattering of Heavy Ions at HIRFL-CSR. Chinese Physics C, 2007, 31(10): 947-951.
[6]	DAI Zhong-Ying , LI Qiang , XIAO Guo-Qing , JIN Xiao-Dong , YAN Zheng . Capability Verification of the Beam Delivery System in the Superficially-Placed Tumor Therapy Terminal at HIRFL. Chinese Physics C, 2007, 31(7): 655-659.
[7]	HUANG Wei-Ling , LI Quan-Feng , LIN Yu-Zheng , LUO Yi-Sheng . Measurement and Calculation of Photoneutrons Produced in the Electron Accelerator for Radiography Application. Chinese Physics C, 2006, 30(S1): 63-65.
[8]	DAI Zhong-Ying , LI Qiang , YAN Zheng , JIN Xiao-Dong , HU Zheng-Guo , XIAO Guo-Qing . Physical Property Measurement of Therapeutic Carbon Ion Beam in the Shallow-Seated Tumor Therapy Terminal at HIRFL. Chinese Physics C, 2006, 30(9): 920-924.
[9]	LI Qiang . Conformal Irradiation to Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System: (II) Feasibility Experiments. Chinese Physics C, 2006, 30(9): 925-929.
[10]	XING Qing-Zi , LIN Yu-Zheng , FU Shi-Nian , FANG Shou-Xian . Study of Simultaneous Acceleration of Positive and Negative Ion Beams by Dynamic Simulation in RFQ. Chinese Physics C, 2004, 28(6): 659-663.
[11]	ZHANG Yuan . Simulation of Beam-Beam Effects in BEPC. Chinese Physics C, 2004, 28(10): 1116-1120.
[12]	CHEN Zhi-Qiang , YE Yan-Lin , LI Chen , YANG Yong-Feng , ZHAN Wen-Long , XIAO Guo-Qing , XU Hu-Shan , GUO Zhong-Yan , LI Wen-Fei , JIANG Dong-Xing , WANG Quan-Jin , ZHENG Tao , , , , . Investigation of PET Imaging Experiment and Monte Carlo Simulation for Cancer Therapy Using Heavy-Ion Beams at HIRFL. Chinese Physics C, 2004, 28(7): 792-796.
[13]	MA Qiu-Feng , JIN Gen-Ming , LI Wen-Jian , LI Qiang , DANG Bing-Rong . Optimization and Comparison of Depth-Dose Distribution of Heavy Ion Beam. Chinese Physics C, 2003, 27(10): 932-935.
[14]	DING Xiao-Ping , KANG Wen . Study of Layout Principle and Simulated Calculation for a Resonant Extraction System. Chinese Physics C, 2001, 25(2): 167-173.
[15]	YU Qing-Chang , XU Tao-Guang . A Soft Modulating and Double-Scattering Beam Delivery System for Proton Therapy. Chinese Physics C, 2001, 25(3): 271-276.
[16]	YU Qing-Chang , KE Xue-Yao . A Proton Beam Delivery System for Conformal Therapyand Intensity Modulated Therapy. Chinese Physics C, 2001, 25(8): 793-798.
[17]	LI Qiang , WEI ZengQuan , LI WenJian . Calculation of Depth-Dose Distribution of Intermediate Energy Heavy-Ion Beam. Chinese Physics C, 2000, 24(5): 414-417.
[18]	Li Qiang , Wei Zengquan , Li Wenjian , Zhou Guangming , Dang Bingrong , Cai Xichen , He Jing , Xie Hongmei , Han Guangwu , Huang Tao , Chen Weiqiang , Wang Jufang , Zhang Shumin . Extending of the Bragg Peak of Heavy lon Beam. Chinese Physics C, 1998, 22(7): 646-650.
[19]	YU Qing-Chang . A DISCUSSION OF TRANSFORMATIONS OF STRIP ION BEAMS INTO AXISYMMETRICAL BEAMS. Chinese Physics C, 1989, 13(2): 106-108.
[20]	YU Qing-Chang . THE MUTUAL TRANSFORMATION OF STRIP ION BEAMS AND AXISYMMETRICAL ION BEAMS. Chinese Physics C, 1984, 8(2): 191-198.

Access

Get Citation

LI Qiang. Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations[J]. Chinese Physics C, 2005, 29(10): 1006-1011.

LI Qiang. Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations[J]. Chinese Physics C, 2005, 29(10): 1006-1011. shu

RIS(for EndNote,Reference Manager,ProCite)

BibTex

Txt

Milestone

Received: 2005-01-11
Revised: 1900-01-01

Article Metric

Article Views(2966)
PDF Downloads(598)
Cited by(0)

Policy on re-use

To reuse of subscription content published by CPC, the users need to request permission from CPC, unless the content was published under an Open Access license which automatically permits that type of reuse.

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations

Corresponding author: LI Qiang,

Institute of Modern Physics,Chinese Academy of Sciences,Lanzhou 730000,China2 German Heavy-Ion Research Center GSI,Darmstadt 64291,Germany

Received Date: 2005-01-11

Accepted Date: 1900-01-01

Available Online: 2005-10-05

Abstract: Within the framework of the pilot heavy-ion therapy facility at GSI equipping an active beam delivery system of advanced raster scanning technique, the investigation of actively conformal irradiation to moving tumors using heavy ions is underway. The influences of target motion on dose homogeneity and conformity degree were theoretically studied under the condition of the active raster-scanning beam delivery system.The relationship between the target motion with different patterns and the uniformities of doses delivered by the raster scanner to different iso-energy slices of the moving target were simulated with an experimentally measured beam spill. Several strategies improving the dose homogeneity in the moving target volume were derived from these simulation results. The simulations presented in this paper provide an effective means for evaluating the dose distribution for a moving target, and the results and implications of this theoretical work establish a substantial basis for feasibility experiments of the compensation for target motion with the active raster scanner at GSI.

HTML

Reference (1)

Conformal Irradiation for Moving Targets in Heavy Ion Radiotherapy with Raster-Scanning Beam Delivery System (Ⅰ) Simulations

Abstract：

References

Access

Article Metrics

Metrics

通讯作者: 陈斌, bchen63@163.com

Email This Article